The  usage of Zanaflex 2mg or Zanaflex 4mg causes a moderate reduction of blood pressure. The simultaneous use of Zanaflex pills with antihypertensive drugs, enhances the anti-hypertensive effect. In the treatment of post-stroke spasticity, a hypotensive effect of Zanaflex tablets may be used either to reduce the dose of antihypertensive drugs, or to stop the anti-hypertensive therapy, conducted before.